1798 was an important year for Edward Jenner, a country Doctor from Berkely in Gloucestershire. Already a fellow of the Royal Society after discovering anti-social nesting behaviour of cuckoos, Jenner published a paper documenting his success using the mild cowpox virus to immunise his patients against smallpox. This programme examines the life and achievements of this great but elusive man, who changed the course of history. Follow in Edward Jenner's footsteps around the beautiful Glouscestershire countryside, the places of his childhood, fossil hunts and nature studies. See the London hospitals where he trained in the latest surgical procedures of the day, before returning to 'The Chantry', his beloved country home. This beautiful house, now the Jenner Museum, contains many of the instruments Jenner used in his experiments as well as his letters and papers. 1798 may well have been an important year for Edward Jenner, but for the rest of the world it marked one of the major breakthroughs in medical history.