Investigative reporter Emanuelle (Laura Gemser) finds herself locked up in an all women penitentiary run a ruthless warden and her brutally sadistic guards. Vowing to exact revenge upon the corrupt politician who set her up, Emanuelle must first survive the daily torture and attempts at her life by grotesque prison bully Albina. Into this powder keg of sex and violence comes four bloodthirsty death row inmates led by "Crazy Boy" Henderson (Gabriele Tinti/Emmanuelle and the Last Cannibals). Blasting their way to a prison takeover, this quartet of psychotic criminals takes advantage of the all-female situation, only to find they have bitten off more than they can chew. With the police launching an all-out assault upon the rampaging inmates, Emanuelle battles to stay alive amidst the bloodshed and depravity...and the most horrifying game of Russian Roulette ever seen!