Alex Winter stars as Ricky Coogan, a trade spokesperson sent to South America to help sell a plan to dump a toxic chemical there. Along with his friend, Ernie, and would-be girlfriend and environmental protester, Julie, he visits the test centre. The three of them gain first hand experience of the chemical's effect when they discover the test centre is a mutant freak farm! When they are taken prisoner by the proprietor and evil scientist, Elijah C Skuggs (Randy Quaid), the consequences are hilarious! Skuggs uses the very chemical they were sent to promote to diffuse Ernie and Julia into Siamese twins whilst the obnoxious Ricky is turned into a half man half beast!