In their battle against the armies of Lordgenome, Team Dai-Gurren has suffered a crippling blow with the death of Kamina. Simon must now pull himself together and emerge from the depths of depression in which he finds himself wallowing. Will a chance meeting with a beautiful Nia, found inside a discarded crate, be the key to getting Simon back on his feet? And who is the mysterious girl and what is her connection to Lordgenome? Get ready for the final battle of the human race against the beastmen and prepare to glimpse into the future that Team Dai-Gurren is creating for mankind.