Two years after losing contact, Akira discovers that his long-lost brother has been seen on a remote island that does not even exist on the map! He decides to investigate the story with several friends. They find their way to Higanjima a dark and mysterious place, but what has happened to the island's inhabitants? They learn too late that they have been lured into a trap and are quickly surrounded by blood-thirsty vampires. Now the friends must fight for their survival and find a way to escape from Higanjima - Vampire Island.