Something strange is going on at the Littlest Pet Shop. Russell decides to hitch a ride to school with Blythe and instantly gets lost. Blythe loses her necklace in a batter for cupcakes that are meant to go to the Biskit twin s party. And to make things truly disastrous, Blythe loses her ability to understand her pet friends, is it caused by her mystery illness? Will she ever be able to understand her pet pals again?