I Meet Elizabeth McCord (Tea Leoni): wife, mother, Ph. D., former CIA analyst... and now, America's newest Secretary of State. She left the world of covert intelligence behind for ethical reasons to lead an academic lifestyle with her supportive husband Henry (Tim Daly) and her teenage children. Now the President needs her, and he knows from experience that Elizabeth has the knowledge and tenacity to advise on and steer the nation's foreign policy. Facing international crises - from embassy bombings to treaty negotiations - Elizabeth's maverick style puts her at odds with the President's Machiavellian Chief of Staff, Russell Jackson (Zeljko Ivanek). Earning the grudging respect of State Department insider Nadine Tolliver (Bebe Neuwirth), Elizabeth adapts to political manoeuvring while uncovering dark secrets that threaten to unravel the administration.