London is nervous at a series of 'pyjama suicides' - a rash of self-inflicted deaths of prominent people in the dark hours of the night. Where is Sherlock Holmes? On a fishing holiday in Scotland with Watson of course. The lack of suicide notes convinces Holmes that these are murders 'There's something uncanny about this - monstrous and horrible.' Holmes discovers that the victims all liked to gamble and disguises himself as an Indian officer and at a Posh London Casino where he meets the fascinating Adrea Spedding whom Holmes is convinced is behind the killings. A series of disguises and deadly game playing ensues as Holmes and Watson enter a battle of wits with The Spider Woman.