Running away from a psychotic husband, Kate Frazier (Kelly Macdonald) flees to Chicago. She keeps her distance from the people she meets, and avoids questions about her recent past. Kate has a chance-meeting with an assassin, Frank Logan (Michael Keaton), just minutes after a cold-kill. This unlikely pair, haunted by the life-choices they have made, seem destined to save each other. But, events unfold and the painful truth emerges.