Eliseo (Javier Camara) is ugly, lame and single. He still hasn't found the woman of his dreams and he doesn't really know what love is. Nati (Carmen Machi) is similarly ugly, she's missing one breast and is currently separated. She's just met the man of her dreams but she doesn't know what real love is either. Eliseo, on the other hand, fears that the worst is just around the corner, whilst Nati fantasises that the best is yet to come. When Eliseo's mother dies, their two paths cross for the first time in twenty years, giving them one last chance to find happiness and love. But what happens when your ideal woman is married to your brother?