The boys are separated when kidnappers take Al to their hideout, leaving Ed frantic to find his brother. Izumi steps in to help her protégés as always, and finds they've learned something from life she could never have taught them alone… responsibility. Major Armstrong battles Greed's men in the sewers in an attempt to save Al, while up above, Ed escapes the military's clutches for a showdown with Greed. As Lust suggests the battle is part of some larger plan, Greed morphs his body into an impervious shield, and swears Ed must kill him if he wants to see Al again. Lust and Gluttony meet Wrath for the first time and quickly set out on the Elric brother's trail. Will Ed and Al reach their destination before they're overtaken? And if they do, are they ready for what they'll find?