Times are tough at Babylon, the brilliant new manager, Juliet Miller, nicknamed "The Undertaker", is charged with preparing the hotel for sale. Then, who should stroll in through the hotel doors but dishy, multi-millionaire playboy Sam Franklin - Juliet's once penniless ex-husband. Setting hearts a flutter, he soon seems interested in more than just a suite at the hotel. Meanwhile, it's down to the staff to keep Hotel Babylon afloat: the ever-charming concierge Tony; newly-promoted head of housekeeping Tanya; flamboyant head barman Gino; the even more flamboyant receptionist, Ben; and, keeping tongues wagging, a now heavily-pregnant head receptionist Anna. Together, the team face a terrorist threat that grips London; see two arch rival boxers booked into its suites; host a celebrity magazine shoot and stage a fabulous Bollywood style wedding - all accompanied by the usual Hotel Babylon schemes, antics and affairs. As Sam's interest in the hotel - and Juliet - grows, she is determined not to let him get under her skin again. But with so much unfinished business between them, will she be able to stop herself?