"Khiladiyon Ka Khiladi" is about the deadly game of survival in a ruthless world of crime and sleaze. Akshay (Akshay Kumar) who is an army officer is on his way to U.S.A. to attend his brother, Ajay's (Inder Kumar) wedding, on the flight meets Priya (Raveena Tandon) and it is love at first sight for both of them. But tragedy awaits Akshay in America. His brother is missing and is wanted by the American Police. Akshay's search for his brother leads him to the dangerous Maya (Rekha) who is above even the American Law. An untouchable. Thus starts a game of life and death. The player involved will have only one chance.