Doug (RJ Mitte) is an intelligent but sheltered college student with muscular dystrophy. His static life changes forever when he hires underachieving classmate Scott (Ray William Johnson) as his driver. Doug agrees to accompany Scott on a road trip to Las Vegas in order to escape his oppressively loving mother (Daphne Zuniga) and to get closer to his college crush Stephanie (Paloma Kwiatkowski), who ends up tagging along. At the height of the journey, a tragic series of events tests their bond and opens the road to self-discovery. Drugs, gambling, and romance await the three friends in this unflinchingly honest American coming-of-age drama.