In a secluded army research centre, observers look on in stunned silence as Lt. Col. John Reynolds' brainchild, 2-4-5 Trioxin, re-animates a decaying corpse and transforms it into a deadly, bio-weapon. But unbeknown to the military they are not alone. The Colonel's son, Curt and his girlfriend Julie are also in the lab and they too witness Trioxin's incredible power. Fleeing in disbelief from what they have seen the couple are involved in an horrific motorcycle smash and Julie is killed. Curt knows what he must do - bring the love of his life back from the dead using his father's secret weapon. But instead of the girl he knew, Julie is reincarnated as the living dead - an indestructible ghoul with a bite that turns her victims into zombies hungry for human flesh.