Featuring cases, characters and events taken from the London Hospital records, nurse's ward diaries and intimate memoirs, these gritty medical series show the lives - and forbidden romances -of pioneering doctors and nurses a hundred years ago. Run with a will of iron by formidable Matron Eva Luckes, the hospital in London's poverty-stricken East End deals with anything from infectious diseases like syphilis, pneumonia and tuberculosis to shocking injuries of the times such as self-abortion injuries, victims of anarchist bombings and an East End gang member wounded in a shooting. For the nurses and doctors - including Nurse Russell, Dr. Culpin, Nurse Bennett, Dr. Walton and the surgeons Huriy Fenwick and cocaine-addicted Dr. Dean - work is tough and relentless. Relationships between staff might be strictly forbidden, but romance continues to blossom away from the Matron's gaze. In a time of great change, the hospital constantly faces up to the future. Pioneering radiographers work with the perilous x-ray equipment, scandalously dangerous chloroform used as anaesthetic and revolutionary new electro-mechanical devices are instigated. Equally edgy and heart-warming, these series bring the Edwardian hospital compellingly to life - illuminating the dramas and romances of a fascinating medical era.