Harley Street is a glossy, sexy and modern drama set in London's famous medical district. Together the team at Harley Street handle difficult and life-threatening cases, made more traumatic since their parents are often known and trusted friends. They rely on each other completely for mutual support. The snag is Martha and Robert used to be lovers and 195's professional rival Dr Felix Quinn (Oliver Dimsdale) soon becomes a rival for beautiful Martha's heart. The doctors at 195 Harley Street must meet intense medical challenges whilst ensuring their personal lives are not put on the critical list.