Ex-mobster Bill "The Mouth" Manucci has double-crossed 'The Skipper', one of Chicago's toughest crime bosses and made off with a cool $12 million. Even an anonymous life in rural South Carolina with the help of the Federal Witness Protection Program isn't enough to keep The Skipper from tracking him down. A gang of mob henchmen led by Miles are sent to collect the stolen cash and teach Bill a lesson. A run-in with the corrupt local Sheriff Dex leads to a destructive detour via a crystal Methane factory and some very upset rednecks. With the mob, the sheriff and a bunch of rednecks on his tail, Bill is forced to put his trust in ex-partner Miles and his wife. The trouble is, now nobody knows who is on which side.