The craftmanship and art of handmade manga and computer graphics unite, in this psychological thriller about a surgeon with the hands of God. Black Jack is an underground, master surgeon who possesses impeccable skills, enabling him to perform operations that are impossible for most. He is a man alone and full of mystery, appearing in operating rooms to fulfil his tasks, only to vanish into thin air. Now he is faced with his most difficult task to date and must challenge the limits of medical science... before it's too late! An extraordinary number of intellectual and athletic 'Super Humans' have the world caught in awe, wonder and excitement. These 'Super Humans' far exceed the framework of common sense and possess the ability to outperform all of their rivals... but how did they get this way? Black Jack discovers the truth behind this unusual occurrence... a hideous conspiracy lurking behind this strange genetic phenomenon... and a dark secret that is about to endanger the existence of all mankind.