Dylan Jameison (Michael Angarano) is a 16 year-old kid with terminal cancer who's living life as fast as he can. When a charitable organization, "United Wish Givers," grants him a last wish, he initially chooses to go fishing with his football hero, Jason O'Malley. But that's not what he really wants. In a moment of inspiration during the televised news conference, Dylan reveals that his true final wish is to spend a weekend with supermodel Nikki Sinclair (Sunny Mabrey). With the help of his two best friends. Slap and Ricky, and Jason O'Malley (Johnny Messner), Dylan spends his last days in Manhattan, trying to fulfil his wish, to the dismay of his single mom, Karen (Cynthia Nixon). In addition to the usual growing pains encountered by a boy his age, Dylan is faced with coming to terms with his imminent departure from this world. His resulting journey is both touching and surprisingly funny.