Detective Eddie Boone (James Black) is on a stake out of a notorious drug dealer. But things go badly wrong during the ambush and Eddie is injected with a new drug called Ozone, which eventually turns its victims into zombies. His partner and friend Mike Weitz (Tom Hoover) is kidnapped by a group of Ozone addicted zombies. Desperate to save his partner from the marauding zombies, Eddie searches the streets. But as he kills any zombie that gets in his way, the effect of the Ozone drug in his blood starts to take effect moving Eddie one step closer to becoming a zombie himself.