The Creature from the Black Lagoon 'resurfaces' when he is captured in his Amazonian home by a team of researchers and transported to a holding tank in a Florida marine park. Once imprisoned, the 'Gill Man' becomes the subject of crude and cruel experiments conducted by his supposedly superior human captors. But the tormented Creature begins to emerge as a hauntingly beautiful alien, and a female researcher (Lori Nelson) forms an uneasy emotional link with him, as her own doubts about career vs. motherhood parallel the Creature's feelings of alienation and confinement. Soon they are both driven to break free of their respective 'prisons' with exciting results. 'Revenge of the Creature' is full of surprises, not the least of which is Clint Eastwood in his first screen appearance as a technician who has trouble holding onto a laboratory mouse.