A remake of the 1971 classic film, this is the true story of a special relationship between two professional football players, Gale Sayers (Mekhi Phifer) and Brian Piccolo (Sean Maher). The star players for the Chicago Bears, Sayers and Piccolo soon become roommates and best friends. When Sayers suffers a knee injury in mid-season, it is Piccolo who prods and inspires him to work toward a complete recovery. Then fate deals a cruel blow: Piccolo is stricken with malignant cancer. The constant support and friendship of Sayers plays an important role in Piccolo's heroic fight against the disease.