Researchers in the undersea laboratory Aquatica have genetically altered the brains of captive sharks to develop a potential cure for Alzheimer's disease. There is one unexpected side effect: the sharks are getting smarter. Which could mean trouble for the researchers. And lunch for the sharks. You can swim but you can't hide when a tropical storm floods Aquatica, plunging Samuel L. Jackson, Saffron Burrows, Thomas Jane, L.L. Cool J, and the rest of the crew into a harrowing battle of wits against sleek killing-and thinking!-machines.