Encompassing a single, fateful evening in the sprawling city of Sao Paulo, 'Jorurney to the End of the Night' is a gritty crime thriller centering around an illicit drug transaction gone awry. Two Americans in exile - Rosso (Scott Glenn) and his son, Paul (Brendan Fraser) - have been carving out a life in Brazil running a nightclub-brothel, but they both harbor dreams of getting out of the business once and for all. Then, one night, it seems their prayers are answered when a customer leaves behind a suitcase in the club which contains the means for Rosso and Paul to change their lives for ever. Rosso will take his beautiful, young wife Angie (Catalina Sandino Moreno) and their 5 year-old son, Lazare, to start over in a new city, far away. Paul will escape mounting debt, an escalating cocaine habit, and finally be rid of his father (whom he despises and blames for all of his problems). It all depends on one person - a Nigerian immigrant named Wemba (Mos Def) who must make his way safely through the perilous world of nocturnal Sao Paulo.