Craig Schwartz (John Cusack) is a struggling street puppeteer. In order to make some money, Craig takes a job as a filing clerk. One day he accidentally discovers a door...a portal into the brain of John Malkovich (played by John Malkovich)! For 15 minutes, he experiences the ultimate head trip – He is being John Malkovich! Then he's dumped onto the New Jersey turnpike! With has beautiful office mate Maxine (Catherine Keener) and his pet-obsessed wife (Cameron Diaz), they hatch a plan to let others into John's brain for just $200 a trip.