Jake Schram (Ben Stiller) and Brian Finn (Edward Norton) are single, successful, extremely popular guys who have been best friends since, well, forever. They are about to be reunited with their other best childhood buddy - the feisty, lanky tomboy, Anna (Jenna Elfman). Anna has grown into a high-powered, workaholic beauty whose re-entry into their lives turns this old circle of friends into a love triangle, a very complicated one at that because Jake's a rabbi and Brian is a priest.
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