Based on William Brinkley's best-selling novel, "The Last Ship" chronicles a global catastrophe that nearly decimates the world's population. Series 2 opens with Captain Chandler (Eric Dane), XO Slattery (Adam Baldwin) and the rest of the crew aboard the Navy destroyer USS Nathan James working to disseminate the cure developed by paleomicrobiologist Dr. Rachel Scott (Rhona Mitra). As soon as they arrive back on U.S. soil, however, they face new threats in the form of a new world order under the leadership of Granderson (guest star Alfre Woodward) and a mysterious new enemy, The Immunes, bent on taking over the world.
Rhona Mitra, Titus Welliver, Eric Dane, Adam Baldwin, Fay Masterson, Alfre Woodard, John Pyper-Ferguson, Sam Spruell, Travis Van Winkle, Jade Pettyjohn, Marissa Neitling, Maximiliano Hernández, Paul James, Bill Smitrovich, Hope Olaide Wilson, Chris Sheffield, Grace Kaufman, Jocko Sims, Alice Coulthard, Charles Parnell
Jack Bender, Tim Matheson, Sergio Mimica-Gezzan, Paul Holahan, Nelson McCormick, Hank Steinberg, Peter Weller, Mario Van Peebles, Olatunde Osunsanmi, Greg Beeman
Eric Dane, Mark Malone, Wayne Carmona, Tony Mark
Steven Kane, Hank Steinberg
Steven Kane, Hank Steinberg, William Brinkley, Nic Van Zeebroeck, Jessica Butler, Jill Blankenship, Onalee Hunter, William Rotko, Anne Cofell Saunders