On the tiny island of Little Happy, Dr. Emma Collins (Tania Raymonde) and her team monitor a flourishing marine nursery where great white sharks come to breed. Their idyllic existence is interrupted when Emma's ex-boyfriend arrives in search of three murderous bull sharks. But these aren't ordinary sharks: Their mother, Bella, was genetically modified to be highly intelligent...and dangerous. As their body count rises, it's clear that Bella's offspring inherited her killer genes, and if they manage to spawn, life as we know it may end. Get ready for the deadliest return to the deep blue sea yet!