Bad luck follows Edward Harrinton (Ron Eldard). Addicted to the bright lights of Las Vegas, he gambles his way further and further into debt. Down on his luck he accepts a job offer from his shady uncle, (Joe Mantegna). The job is 'running' for Deep Thoat (John Goodman) - the most notorious gangster in Vegas, placing bets and collecting the winnings. But Edward isn't too good at keeping hold of cash. His blossoming romance with beautiful waitress Karina (Courteney Cox) means he stands to lose more than just a few dollars. The stakes just got a whole lot higher!