Appropriately enough, 'Naseeb', a story of destiny and fate, begins with a lottery ticket. A drunk who cannot pay his tab trades his 'winning' ticket to the waiter, Namdev, instead. Namdev (Pran), Damu (Amjad Khan), Ragu (Kader Khan) and one other friend decide to go in on the ticket together, but when it turns out to actually be a winner, Damu and Ragu turn on the other two, murdering the one and framing Namdev. Cut to ten years later - Damu and Ragu have used their stolen lottery money to build a fabulous hotel and make millions. Damu has used a share of his money to send his only son, Vicky (Shatrughan Sinha) to school in England. They have even employed Namdev's oldest son Johnny (Amitabh Bachchan), Vicky's best friend, as a waiter in the hotel. By coincidence (or by fate!) John and Vicky fall in love with the same beautiful singer, Miss Asha (Hema Malini). At the same time, John's younger brother Sunny has fallen for Asha's younger sister, Kim (Kim). Kim and Asha also happen to be the daughters of the man Namdev supposedly murdered. The lives of all these characters become intertwined and 'Naseeb' becomes a poignant story about love, friendship, sacrifice and above all, destiny.